What is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide (MDP) involved in cellular stress response and metabolic regulation. It is studied in vitro for its role in activating AMPK pathways, regulating cellular energy metabolism, and supporting mitochondrial peptide signalling research. Supplied as a high-purity lyophilised powder, MOTS-c from Power Peptides is designed exclusively for laboratory-based studies and is not intended for human use.
Research Applications
- Investigation of mitochondrial peptide pathways
- In vitro studies on AMPK activation
- Metabolic and cellular signalling research
- Laboratory exploration of mitochondrial-derived peptides (MDPs)
Key Features
- Available in 10 mg and 40 mg sterile vials
- Research-grade purity: ≥98% (HPLC)
- Lyophilised formulation for research stability
- Batch-specific Certificate of Analysis available
Specifications
| Compound Name | MOTS-c |
|---|---|
| Form | Lyophilised peptide powder |
| Available Amounts | 10 mg / 40 mg |
| Purity | ≥98% (HPLC verified) |
| Appearance | White to off-white powder |
| Solubility | Soluble in bacteriostatic water |
| Storage (unopened) | –20 °C, protected from light |
| Storage (after reconstitution) | 2–8 °C; aliquoting recommended |
| Documentation | Certificate of Analysis available upon request |
Reconstitution & Handling
- Reconstitute with bacteriostatic water or a sterile laboratory solvent
- Swirl gently until fully dissolved
- Aliquot if storing to avoid peptide degradation
Quality & Testing
MOTS-c supplied by Power Peptides undergoes analytical verification using high-performance liquid chromatography (HPLC) and mass spectrometry to ensure ≥98% purity and molecular integrity. Each batch is traceable and supported by a Certificate of Analysis.






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